Mass Flow Controllers Maximize Bioreactor Performance

Protein Design Labs (PDL) has been able to maximize pilot production control by integrating an automated gas mixing system with Sierra Instruments' microprocessor-based mass flow controllers in their B. Braun Biostat fermenter. To minimize foam, PDL needed to reduce the net volume of air and oxygen gases that were being bubbled into the culture medium. Sierra's Model 860 MFCs permit them to flow a precise low volume of air. The controllers also provide an elegant and straightforward method of measuring oxygen uptake rate. Read complete story.